Can you suggest one or more study designs that could be used to determine whether climate change has resulted in more malaria in specific geographic areas?

Suppose you want to study whether global warming is likely to increase human disease. With increased global temperature, one issue is the extension of areas in which mosquitos can live, which in turn can extend the range of malaria and dengue fever. Can you suggest one or more study designs that could be used to determine whether climate change has resulted in more malaria in specific geographic areas? What data would you need? Do you think GIS could be included in your study design?
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